Neurovascular biomarkers and tools (based on CT, MR, US)

Through participation in large scale European projects, public private collaborations and bilateral research agreements with leading research organisations, we can provide services in a wide range of quantitative analysis problems, supporting population and clinical research.

Examples of quantitative imaging biomarkers and tools include:

  • Aneurysm segmentation (CTA)
  • Carotid artery segmentation (CT)
  • Carotid artery plaque characterization (CT/MR/US)
  • Distensibility measurement carotid artery (CTA)

Scientific references

Many of these biomarkers have been documented in peer reviewed papers, thoroughly validated, and applied in the context of population and clinical imaging studies.

  • A. Firouzian et al., Intracranial aneurysm segmentation in 3D CT angiography: Method and quantitative validation with and without prior noise filtering, European Journal of Radiology, 2010
  • A. Arias Lorza et al., Carotid Artery Wall Segmentation in Multispectral MRI by Coupled Optimal Surface Graph Cuts, IEEE Transactions on Medical Imaging, 2015
  • M.J. van Gils et al., Carotid Atherosclerotic Plaque Progression and Change in Plaque Composition over Time: A 5-year Follow-up Study with Serial CT Angiography, American Journal of Neuroradiology, in press
  • Z. Akkus et al., Fully Automated Carotid Plaque Segmentation in Combined Contrast Enhanced and B-mode Ultrasound, Ultrasound in Medicine and Biology, 2015
  • D.D.B. Carvalho et al., Joint Intensity-and-Point Based Registration of Free-hand B-Mode Ultrasound and MRI of the Carotid Artery, Medical Physics, 2014
  • R. van 't Klooster et al., Automated registration of multispectral MR vessel wall images of the carotid artery, Medical Physics, 2013
  • K. Hameeteman et al., Automatic carotid artery distensibility measurements from CTA using nonrigid registration, Medical Image Analysis, 2013
Contact for more information:
or call us at
(+31) 108 41 17 49