Brain Segmentation Software

Your indispensable medical software tool for atrophy quantification and WMH detection


Quantib® ND Plus is our CE marked and FDA cleared
medical software solution offering automated segmentation of
brain structures and white matter hyperintensities 




Accelerated Workflow Icon

Accelerated Workflow

Pre-processing will automatically start after sending the scan to the workstation to ensure the images are analyzed when the user is ready to review.

Accurate Quantification Icon

Accurate Quantification

Quantified segmentation results of brain volumes covering CSF, lobes, hippocampus and WMHs are presented in an easy to read table and visualized with color coded overlays on an anatomical map. 

Elaborate Reporting Icon

Elaborate Reporting

Examination results can be downloaded or uploaded to PACS as a comprehensive report including self-selected cross-sections and personal comments.


Be able to share all your examination results instantly

Download Report

Accelerated and more accurate dementia diagnosis

With this machine learning radiology application, automatic brain tissue segmentation provides fast insight in the possible presence of atrophy related to Alzheimer’s disease or other types of dementia, supporting more accurate diagnosis. The available reference centile curves derived from the population-based Rotterdam Scan Study enable accurate detection and staging of atrophy.


Brain atrophy tracking over time 


Quantib® ND Plus follow-up feature allows for tracking of neurodegeneration over time. Based on T1w scans, the radiology software will be able to process scans from subsequent time points and compare quantified volumes of total brain, CSF, lobes, hippocampus and white matter hyperintensities.


Radiology software to detect and track MS lesions

Automatic assessment of white matter hyperintensity development supports easy and fast monitoring of MS patients. Quantib® ND Plus medical software distinguishes between new and previously identified WMHs, providing an intuitive visualization with colour-coded lesions super positioned on an anatomical map. 

Quantib® ND Plus user interface and manual are available in English, Spanish and French. Quantib® ND Plus manual is available in German and Italian. 

The results table presents quantified brain volumes

Quantib® ND Plus offers a table presenting a clear overview including volumes of ICV, CSF and Total Brain Volume, as well as lobes and hippocampus. Results supported with self-selected cross-sections can be exported to a comprehensive report.

200518 - Results table (1)

The follow-up feature enables quantified atrophy assessment

Atrophy can be monitored using the brain structure segmentation follow-up function. The reference centile curves allow for comparison of patient brain volume development to the expected values for a healthy population. The results table presents quantified values for different brain structures, including all lobes. 

User interface

Longitudinal comparison allows for WMH tracking

Two time point segmentation of white matter hyperintensities supports quantified tracking of lesion development. The WMH results table gives an overview of WMH development in volume and number. 

200518 - WMH Follow up-1 (1) (1)

What do users say about Quantib® ND Plus? 

Curious for more detailed information on Quantib® ND Plus?

We are happy to schedule a call and give you the full tour of all that our machine learning radiology application Quantib® ND Plus offers during a video conference.

Quantib® ND Plus Resources


QND 1.5 Lobes 3

Quantib® ND Plus

Get a comprehensive overview of dementia diagnosis scales, and learn more about software-supported atrophy quantification and white matter hyperintensity detection.


Automatic Analysis of Brain Tissue and Structural Connectivity in MRI

Dive into the method behind the product

"Automatic Analysis of Brain Tissue and Structural Connectivity in MRI", Renske de Boer's thesis, written at Erasmus University Rotterdam, describes the starting point of our Quantib® Brain and Quantib® ND Plus products.

Download THESIS


QND 1.6 Sample report resources (1)


Quantib® ND Plus Sample Report

After analysis Quantib® ND Plus allows you to download an insightful report with a brief overview of quantified results, optional self-selected cross-sections and personal comments.

Download Report


A trick to get the best performance from an AI radiology algorithm: stratification

Dec 17, 2020 4:15:00 AM BY Jim Tol

Quantitative Radiology is Finally Coming

Nov 26, 2020 3:31:29 PM BY Tim Leiner

Subscribe for Updates